Allantoin

Excellent

Extraits végétaux

Allantoin at a glance

  • Occurs naturally in most organisms but can be produced synthetically
  • Has both soothing and moisturising properties for skin
  • Helps mitigate skin’s response to more active ingredients
  • Used in concentrations up to 2% in cosmetics

Allantoin description

Allantoin is a byproduct of uric acid that can be extracted from urea and is the result of metabolic processes that occur in most organisms - among them animals (including humans) and bacteria. It can also be extracted from comfrey (taken from the roots and leaves) and is proven safe and effective because it does not contain the potentially irritating alkaloid compounds that occur in the comfrey plant. Despite the natural source of allantoin being safe, the type of allantoin used in skin care products is generally produced synthetically as this guarantees no impurities while sacrificing none of allantoin’s effectiveness. It serves as an effective soothing agent and has moisturising properties, giving it value especially in products designed to treat sensitive or compromised skin. It can also help mitigate skin’s response to stronger active ingredients and is often included in formulas to help buffer any potential adverse effects. In cosmetics, it is used in concentrations up to 2%, but in clinical settings it can be used in greater amounts, where research has shown it can have an impact on healing. In the United States, it is FDA-approved as an over the counter (OTC) skin protectant in concentrations of 0.5-2%.

Allantoin references

  • Chemistry Series, March 2020, pages 7-21
  • Molecules, June 2019, pages 1-33
  • European Journal of Pharmacology, February 2018, pages 68-78
  • Journal of the American Academy of Dermatology, June 2017, Volume 76, Issue 2, Supplement 1
  • Pharmacognosy Review, Volume 5, July-December 2011
  • International Journal of Toxicology, May 2010, Supplement, pages 84S-97S
  • Journal of Occupational Medicine and Toxicology, October 2008, ePublication
  • https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=347&showFR=1

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Évaluation des ingrédients

Excellent

Ingrédient dont l’efficacité est prouvée et basée sur des études cliniques indépendantes. Un actif exceptionnel pour la plupart des types de peau ou problématiques cutanées.

Bon

Ingrédient nécessaire pour améliorer la texture, la stabilité ou la pénétration de la formule.

Moyen

Généralement non irritant, mais peut présenter des problèmes esthétiques, de stabilité ou autres qui limitent son utilité.

Mauvais

Un risque d'irritation est possible. Ce risque augmente lorsqu'il est associé à d'autres ingrédients problématiques.

Très mauvais

Peut provoquer irritations, inflammations, sécheresse, etc. Peut présenter un certain intérêt, mais s'avère globalement plus nocif que bénéfique.

Inconnu

Nous n’avons pas trouvé cet ingrédient dans notre base de données. Nous enregistrons les ingrédients manquants et mettons régulièrement notre base à jour.

Non évalué

Nous n'avons pas encore évalué cet ingrédient car nous n'avons pas eu l'occasion d'examiner les recherches le concernant.