Genistein

Excellent

Antioxydant

Genistein at a glance

  • Belongs to a set of compounds known as isoflavones, which are sources of phytoestrogens
  • Commonly derived from soy
  • Has antioxidant and skin-soothing properties
  • Has been shown to visibly improve signs of ageing that occur or accelerate during menopause

Genistein description

Genistein is a naturally occurring plant ingredient that belongs to a group of compounds known as isoflavones. Isoflavones are sources of phytoestrogens, also known as plant estrogens, that are not hormones but can connect with receptor sites on skin’s surface, helping it look and feel younger. Genistein is most often derived from soy but can also be produced synthetically (Paula’s Choice Skincare uses the natural variety). As an isoflavone, genistein is a rich source of antioxidants that have impressive skin-soothing properties. Research shows that genistein has multiple benefits for skin, both when it’s ingested and used topically. Applied to skin, genistein exhibits anti-ageing effects, including reducing the visible appearance of wrinkles and helping protect skin from the effects of sun damage. It penetrates skin better than “sister” isoflavone daidzein, but research has shown that these ingredients work even better when paired in a single formula. This is due to the synergy they share as well as both having an affinity for key receptor sites on skin’s surface. Emerging studies also show genistein has a special ability to improve signs of aging and dry skin that are common during menopause. It is typically used in amounts of 0.251% for these benefits, although studies have been done looking at concentrations up to 4%.

Genistein references

  • Phytotherapy Research, March 2020, Volume 34, Issue 3, pages 435-447
  • Surgical and Cosmetic Dermatology, March 2020
  • International Journal of Women’s Dermatology, June 2019, pages 85-90
  • AAPS FarmSciTech, October 2018, Issue 19, Volume 7, pages 3029-3,039
  • Nutrients, June 2017, Volume 9, Issue 6, page 622
  • Journal of Photochemistry and Photobiology B: Biology, March 2015, pages 20-27
  • International Journal of Pharmaceutics, November 2008, pages 36-44
  • The Journal of Nutrition, November 2003, Volume 133, Issue 11, pages 3811S–3819S
  • Journal of Investigative Dermatology, May 2003, pages 835-841

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Évaluation des ingrédients

Excellent

Ingrédient dont l’efficacité est prouvée et basée sur des études cliniques indépendantes. Un actif exceptionnel pour la plupart des types de peau ou problématiques cutanées.

Bon

Ingrédient nécessaire pour améliorer la texture, la stabilité ou la pénétration de la formule.

Moyen

Généralement non irritant, mais peut présenter des problèmes esthétiques, de stabilité ou autres qui limitent son utilité.

Mauvais

Un risque d'irritation est possible. Ce risque augmente lorsqu'il est associé à d'autres ingrédients problématiques.

Très mauvais

Peut provoquer irritations, inflammations, sécheresse, etc. Peut présenter un certain intérêt, mais s'avère globalement plus nocif que bénéfique.

Inconnu

Nous n’avons pas trouvé cet ingrédient dans notre base de données. Nous enregistrons les ingrédients manquants et mettons régulièrement notre base à jour.

Non évalué

Nous n'avons pas encore évalué cet ingrédient car nous n'avons pas eu l'occasion d'examiner les recherches le concernant.