Sulfur

Good

Irritant

Sulfur at a glance

  • Non-metal chemical element
  • Antimicrobial, exfoliating & anti-inflammatory properties
  • Used to treat several skin issues, including acne
  • Typically used in amounts from 3-10%
  • Can cause dryness & irritation in high concentrations

Sulfur description

Sulfur is a non-metal chemical element with the atomic number 16 (meaning it is the 16th element on the periodic table). In its raw form, pure sulfur is a bright yellow, crystalline solid that is colorless and odorless. The traditional “rotten egg” smell commonly associated with sulfur is the result of a chemical reaction involving bacteria. Sulfur has been used since antiquity to treat skin disorders. In modern times, its unique properties are used to alleviate symptoms of several skin conditions, including psoriasis, rosacea, seborrheic dermatitis, and acne. [br] [br] Sulfur’s value in dermatologic practice stems from its antimicrobial and anti-inflammatory properties. Regarding acne, sulfur is also used due to its keratolytic effect, promoting the shedding of dead cells from skin’s surface (in other words, it is an exfoliant). Quick note on the difference in exfoliating action between sulfur and salicylic acid: the latter is considered more effective since it’s oil-soluble and able to penetrate into the pore lining where clogs develop. In contrast, sulfur is water-soluble so primarily acts on skin’s surface to break the bonds holding dead cells and encourage shedding. Sulfur is included in the United States FDA’s Over the Counter (OTC) Acne Drug Products Monograph as one of five approved active ingredients for topical acne treatment. It joins the ranks of benzoyl peroxide, salicylic acid, resorcinol, and resorcinol monoacetate. The monograph establishes guidelines for acceptable ingredients, concentrations, product forms, required labeling, and usage conditions for OTC acne products. Approved concentrations of sulfur for acne products, both rinse-off or leave-on, is 3–10%. Pharmacists can compound topical prescriptions with sulfur and other medications, but there are also numerous over-the-counter products containing sulfur. Since sulfur can be drying for some people’s skin, it is important that you choose products that do not contain harsh or irritating ingredients (and many of them do, so check labels carefully), as they will counter the benefits you want from using sulfur. Also worth noting: sulfur can pose a risk of skin irritation when used in high concentrations and frequent use. Amounts between 3-5% tend to provide benefits with minimal to no risk of dryness or irritation.

Sulfur references

  • Journal of Cosmetic Dermatology, August 2025, pages 1-6
  • SKIN The Journal of Cutaneous Medicine, May 2025, pages 2,275-2,284
  • Chronicles of Clinical Reviews and Case Reports, July 2024, pages 1-19
  • AIMS Microbiology, November 2021, pages 481-498
  • Journal of Clinical and Aesthetic Dermatology, May 2021, pages 32–40

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings

Best

Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.

Good

Necessary to improve a formula's texture, stability, or penetration.

Average

Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.

Bad

There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.

Worst

May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.

unknown

We couldn't find this in our ingredient dictionary. We log all missing ingredients and make continuous updates.

Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.