Tridecapeptide-1 Excellent Peptide Anti-âge Hydratation Tridecapeptide-1 at a glance Helps improve the appearance of wrinkles Can also visibly improve rough texture Has benefits immediately and over time Tridecapeptide-1 description Tridecapeptide-1 is a synthetic patented peptide composed of a unique folded and encapsulated combination of the amino acids alanine, leucine, lysine, and valine. It has clinically proven wrinkle-smoothing action that produces visible results within 15 minutes of application. Over time, its line-smoothing benefits continue, leading to less visible wrinkles, including around the eyes and mouth. This targeted signal peptide works by influencing acetylcholine receptors within skin’s uppermost layers, helping to interrupt the process that leads to the appearance of expression lines. It also helps improve rough texture after four weeks of twice-daily use. Recommended usage levels of tridecapeptide-1 range from 1–10% in leave-on skin care products. Clinical data from the supplier has shown this ingredient’s efficacy is improved when paired with glycols used between 2–5%. *Note:* This ingredient’s name is one that’s known to be misused by disingenuous third-party suppliers looking to get their product into the marketplace sooner. Since Paula’s Choice uses this ingredient, we want to assure you that we’re purchasing direct from the originator of this peptide. Its ingredient name reflects the 13 amino acids present in the sequence, and the “-1” suffix simply differentiates it as the first International Nomenclature Cosmetic Ingredient (INCI) system registration of this name. The “=1” designation does not correlate to the amino acid sequence. Related ingredients: Peptides Amino Acids